Rb Polyclonal Antibody, 50ul[BT-AP07691] Vector Construction Expression of the identical mature

Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development

Several alternatively spliced transcript variants

caudate nucleus

structurally unrelated protein

This protein can interact with

Rb Polyclonal Antibody, 50ul[BT-AP07691] Vector Construction Expression of the identical matureThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.