TRPM4 Rabbit Polyclonal Antibody, 100ul Filtration and immunomodulation

and immunomodulation

This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas

like most family members

The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors

This gene is part of a cluster of MMP genes on chromosome 11

TRPM4 Rabbit Polyclonal Antibody, 100ul Filtration and immunomodulationThe protein encoded by this gene is a calcium activated nonselective ion channel that mediates transport of monovalent cations across membranes thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration but this channel does not transport calcium.