InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection This gene localizes within the

This gene localizes within the class III region of the MHC on the short arm of chromosome 6

5'-tetraiodothyronine

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

It targets receptors for degradation in lysosomes

InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection This gene localizes within theThe protein ITPKB encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5 trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium calmodulin and protein phosphorylation mechanisms control its activity.