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KLHL3 Polyclonal Antibody, 100ul Cell Transfection This gene belongs to the

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KLHL3 Polyclonal Antibody, 100ul Cell Transfection This gene belongs to theKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare

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Description

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

increased T-cell susceptibility to apoptosis

These desmosomal family members

which is a critical step for extravasation or metastasis

KLHL3 Polyclonal Antibody, 100ul Cell Transfection This gene belongs to theKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare

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