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NVL Polyclonal Antibody, 100ul Centrifuges This gene encodes the nuclear

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NVL Polyclonal Antibody, 100ul Centrifuges This gene encodes the nuclearNVL encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983,

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Description

This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene

The TRIM family is characterized by a signature motif composed of a RING finger| one or more B-box domains| and a coiled-coil region

including lipogenesis and cholesterogenesis

which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes

The encoded protein usually remains with the mother centrosome after centrosomal duplication

NVL Polyclonal Antibody, 100ul Centrifuges This gene encodes the nuclearNVL encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983,

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