GDNF Polyclonal Antibody, 50ul Palm Micro Centrifuges each member of this subfamily

each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted

subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit

It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units

A mutation in this gene is associated with autosomal dominant cerebral ataxia

PTM:Phosphorylated on tyrosines by Syk

GDNF Polyclonal Antibody, 50ul Palm Micro Centrifuges each member of this subfamilyThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. The recombinant form of this protein, a highly conserved