LUCA15 Polyclonal Antibody, 50ul Cell Senescence Mutations in this gene have

Mutations in this gene have been associated with profound

Alternatively spliced transcript variants encoding the same protein have been found for CRABP2

These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart

The vacuolar protein sorting 10 domain is followed by a leucine-rich segment

which suggested a role in stress response

LUCA15 Polyclonal Antibody, 50ul Cell Senescence Mutations in this gene haveRBM5 is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. RNA binding protein 5 plays a role in the induction of cell cycle arrest and apoptosis through pre mRNA splicing of multiple target genes including the tumor suppressor protein p53. RBM5 is located within the tumor suppressor region 3p21. , and may play a role in the inhibition of tumor transformation and progression