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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilon

SKU: 49572680560

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SEK162.00 SEK196.00

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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilonTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

which together with CD3-epsilon

and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway

Alternative splicing results in multiple transcript variants that encode different protein isoforms

B-cell linker bridges B cell receptor-associated kinase activation with downstream signaling pathways

as described in human patients with lissencephaly

A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilonTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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