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CNOT2(Phospho Ser101) Polyclonal Antibody, 50ul Monoclonal Antibodies All MAGUKs contain a PDZ-SH3-GUK

SKU: 48996447018

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USD185.00 USD222.00

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CNOT2(Phospho Ser101) Polyclonal Antibody, 50ul Monoclonal Antibodies All MAGUKs contain a PDZ-SH3-GUKThis gene encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.

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Description

All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies

The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates

A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins

May play a role in tumor angiogenesis

The frame handle supports aseptic operation

CNOT2(Phospho Ser101) Polyclonal Antibody, 50ul Monoclonal Antibodies All MAGUKs contain a PDZ-SH3-GUKThis gene encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.

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