TPH1 Polyclonal Antibody, 100ul[BT-AP09150] Bio-Reaction Tube GO annotations related to this

GO annotations related to this gene include lipid binding

tissue specificity:Detected in breast

Mutations in this gene are associated with gastrointestinal stromal tumors| mast cell disease| acute myelogenous lukemia| and piebaldism

Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene

Frequent amplification of this gene has been found in human tumors

TPH1 Polyclonal Antibody, 100ul[BT-AP09150] Bio-Reaction Tube GO annotations related to thisTPH1 (tryptophan hydroxylase 1) encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in TPH1 have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and