HBP1 Polyclonal Antibody, 100ul[BT-AP03903] Vacuum Filter Many malignant cells secrete the

Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells

Mutations in ABCB7 have been associated with mitochondrial iron accumulation and isodicentric (X) (q13) and sideroblastic anemia

intracellular Ca2+ mobilization

this protein inhibits p53 by binding its transcriptional activation domain

The encoded protein forms a stoichiometric complex with the mTOR kinase

HBP1 Polyclonal Antibody, 100ul[BT-AP03903] Vacuum Filter Many malignant cells secrete theTranscriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5' TTCATTCATTCA 3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.