Raf-1 Polyclonal Antibody, 50ul[BT-AP13533] Measuring Instruments The enzyme specifically cleaves ubiquitin

The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates

This protein has strong similarity to Mus musculus and Cricetulus griseus proteins

which is known for regulating the energy balance of mitochondria under stress

Alternatively spliced transcript variants

This gene may be associated with myelodysplastic syndrome

Raf-1 Polyclonal Antibody, 50ul[BT-AP13533] Measuring Instruments The enzyme specifically cleaves ubiquitinThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.