DOT1L Polyclonal Antibody, 50ul Serological Pipets The isoforms

The isoforms

The tumor necrosis factor superfamily member 4 functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases

and protein kinase C in vitro

GO annotations related to this gene include oxidoreductase activity

DOT1L Polyclonal Antibody, 50ul Serological Pipets The isoformsThe protein encoded by this gene is a histone methyltransferase that methylates lysine 79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.