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ANTR1 Polyclonal Antibody, 100ul Culture Tubes The encoded protein is a

SKU: 46320747789

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ANTR1 Polyclonal Antibody, 100ul Culture Tubes The encoded protein is aThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol

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Description

The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin

Among its related pathways are MAP Kinase Signaling andTGF-Beta Pathway

MIM 163729)| and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures| thereby attenuating ENOS-dependent NO production

|Contains 9 SRCR domains

Mutations in PDHA1 are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

ANTR1 Polyclonal Antibody, 100ul Culture Tubes The encoded protein is aThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol

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