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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in both

SKU: 46307822484

4.6
PLN153.50 PLN175.50

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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in bothThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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Description

which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions

This encoded protein can form a complex with the Golgi matrix protein GOLGA2

The encoded protein is postranslationally glycosylated and localized to the lysosome

Sulfatases hydrolyze sulfate esters from sulfated steroids

This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14

Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in bothThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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