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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis EF-hand calcium binding domain 5)

SKU: 45561258617

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USD162.00 USD193.00

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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis EF-hand calcium binding domain 5)The protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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Description

EF-hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes

a region which confers cyclic nucleotide regulation of message decay

but studies of other populations have not been able to replicate this association

Defects in VCL are the cause of cardiomyopathy dilated type 1W

it ensures optimal cell growth and viability

PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis EF-hand calcium binding domain 5)The protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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