NMBR Polyclonal Antibody, 100ul[BT-AP06070] Hybridoma Antibody Sequencing The protein encoded by the

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system

This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus

and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis

In addition to an F-box domain| the encoded protein contains at least 9 tandem leucine-rich repeats

Isoform 1 is expressed in liver at very low levels

NMBR Polyclonal Antibody, 100ul[BT-AP06070] Hybridoma Antibody Sequencing The protein encoded by theNMBR encodes a 7 transmembrane G protein coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a