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MPRD Polyclonal Antibody, 100ul Immunology The protein encoded by FGFRL1

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MPRD Polyclonal Antibody, 100ul Immunology The protein encoded by FGFRL1This gene encodes a member of the P type lectin family. P type lectins play a critical role in lysosome function through the specific transport of mannose 6 phosphate containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene

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Description

The protein encoded by FGFRL1 (fibroblast growth factor receptor-like 1) is a member of the fibroblast growth factor receptor (FGFR) family

MED11 is a component of the Mediator complex

with subsets of five C-terminal serine residues phosphorylated by different protein kinases

This gene is a candidate gene for RET-associated diseases

Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis

MPRD Polyclonal Antibody, 100ul Immunology The protein encoded by FGFRL1This gene encodes a member of the P type lectin family. P type lectins play a critical role in lysosome function through the specific transport of mannose 6 phosphate containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene

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