HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody, 20ul Immune Repertoire Sequencing These proteins are cleaved by

These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit

However| it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer| stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways| such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase

A processed pseudogene of this gene has been found on chromosome 1

EEF2K encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division

Gene Ontology (GO) annotations related to RAB35 include GTP binding and calmodulin binding

HNF-4 alpha (Acetyl Lys106) Polyclonal Antibody, 20ul Immune Repertoire Sequencing These proteins are cleaved byThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin