PNKP Polyclonal Antibody, 50ul Site-directed Mutagenesis Belongs to the cyclophilin-type PPIase

Belongs to the cyclophilin-type PPIase family

The RAB family of small G proteins regulates intercellular vesicle trafficking

this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF

Has over 50-fold higher inhibitory activity when phosphorylated

The alpha subunit includes the skeletal muscle and hepatic isoforms| and the hepatic isoform is encoded by this gene

PNKP Polyclonal Antibody, 50ul Site-directed Mutagenesis Belongs to the cyclophilin-type PPIaseThis locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.