TRIM2 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos and a 12-kD gamma subunit

and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al

and mediate signal transduction from members of the TNF receptor superfamily

Alternative splicing results in transcript variants

Alternatively spliced transcript variants have been described for DUS2

High mobility group box 1 plays a role in several cellular processes

TRIM2 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos and a 12-kD gamma subunitThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3 ubiquitin ligase in proteasome mediated degradation of target proteins. Mutations in this gene can cause early onset axonal neuropathy. Alternative