EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This gene is a member

This gene is a member of the neuronal calcium sensor gene family| which encode calcium-binding proteins expressed predominantly in neurons

This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)| and in addition to a role in adhesion| it may serve as an accessory molecule for IEL activation

The type I isoform encoded by ARG1

G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity

Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis

EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This gene is a memberEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.