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ARK-1 Polyclonal Antibody, 50ul[BT-AP00610] Modification Enzymes Type II (atypical) cadherins are

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ARK-1 Polyclonal Antibody, 50ul[BT-AP00610] Modification Enzymes Type II (atypical) cadherins areThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins

The product of this gene is required for stem-cell maintenance in the central nervous system| and also regulates gene expression in the stomach

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

PubMed: 19208651)

|disease:In B-cell leukemia (B-CLL) cell line| LB40 and EB308| can be found after heterogeneous chromosomal aberrations| such as internal deletions

ARK-1 Polyclonal Antibody, 50ul[BT-AP00610] Modification Enzymes Type II (atypical) cadherins areThe protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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