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L-type Ca++ CP Gamma7 Polyclonal Antibody, 50ul Buffers & Solutions Adaptor proteins TRAF2 and TRAF5

SKU: 40892971905

4.5
SEK162.00 SEK184.00

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L-type Ca++ CP Gamma7 Polyclonal Antibody, 50ul Buffers & Solutions Adaptor proteins TRAF2 and TRAF5Voltage dependent calcium channel gamma 7 subunit encoded by CACNG7 is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. CACNG7 is part of a functionally diverse eight member protein subfamily of the PMP 22 EMP MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit.

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Description

Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor

and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex

This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb

Detected at very low levels in brain

VitroGel 3D High Concentration comes with VitroGel Dilution Solution (contains sucrose for best osmolarity) to adjust the final hydrogel strength from 10 to 4000 Pa

L-type Ca++ CP Gamma7 Polyclonal Antibody, 50ul Buffers & Solutions Adaptor proteins TRAF2 and TRAF5Voltage dependent calcium channel gamma 7 subunit encoded by CACNG7 is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. CACNG7 is part of a functionally diverse eight member protein subfamily of the PMP 22 EMP MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit.

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