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ANXA8 Rabbit Polyclonal Antibody, 100ul Drying & Desiccation and may play a role

SKU: 40613080744

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ANXA8 Rabbit Polyclonal Antibody, 100ul Drying & Desiccation and may play a roleThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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Description

and may play a role in proliferation

Mutations in this gene are associated with ectodermal dysplasia

Inhibits colony formation in cultured breast cancer cells

Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases

but translocates to the cytoplasm at the start of S phase

ANXA8 Rabbit Polyclonal Antibody, 100ul Drying & Desiccation and may play a roleThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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