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ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this gene

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ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this geneATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

A mutation in this gene was found in individuals with dementia with Lewy bodies

The protein encoded by PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis

alpha actinin isoform that is expressed in both skeletal and cardiac muscles

Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol

Diseases associated with SUPT3H include blastic plasmacytoid dendritic cell

ATP-citrate synthase Monoclonal Antibody, 100ul Electronic Pipette A mutation in this geneATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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