SOS1 Polyclonal Antibody, 20ul Cytokines suggesting that this protein may

suggesting that this protein may be a potential tumor suppressor

Two alternatively spliced transcript variants of this gene

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors

Overexpression of PBK has been implicated in tumorigenesis

which is involved in cellular growth

SOS1 Polyclonal Antibody, 20ul Cytokines suggesting that this protein mayThis gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.