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a basic helix-loop-helix transcription factor

During T-cell activation| this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site| suggesting a negative regulatory role in adaptive immune response

This protein is commonly used as a biomarker of neuronal damage

ay be involved in transcriptional regulation

PPR17 Rabbit Polyclonal Antibody, 100ul Supplements Elevate your research game withThe protein encoded by this gene is found primarily in cerebellar Purkinje cells where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene.