GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization PubMed: 18503084

PubMed: 18503084

Rotor capacity: Micro-plates

also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein)

providing potent enzymatic action to quickly and effectively break down proteins

GO annotations related to this gene include calcium ion binding

GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization PubMed: 18503084The product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.