ACSL3 Polyclonal Antibody, 20ul Serum Mutations in this gene have

Mutations in this gene have been linked with Li-Fraumeni syndrome

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

mitochondrial F1 complex

This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due

The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes

ACSL3 Polyclonal Antibody, 20ul Serum Mutations in this gene haveThe protein encoded by this gene is an isozyme of the long chain fatty acid coenzyme A ligase family. Although differing in substrate specificity subcellular localization and tissue distribution all isozymes of this family convert free long chain fatty acids into fatty acyl CoA esters and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain and preferentially utilizes myristate