TFIIB Monoclonal Antibody, 50ul[BT-MCA1197] Cell Culture Dishes a glycine- and serine-rich region

a glycine- and serine-rich region (called the GS domain) preceding the kinase domain

Mutations have been associated with X-linked dyskeratosis congenita

a type II keratin

and by promoting mRNA binding

This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ)

TFIIB Monoclonal Antibody, 50ul[BT-MCA1197] Cell Culture Dishes a glycine- and serine-rich regionThis gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.