EpoR(Phospho Tyr426) Polyclonal Antibody, 20ul Centrifuges The encoded protein is the

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family

High levels of expression of SGK1 may contribute to conditions such as hypertension and diabetic nephropathy

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suggesting a role in regulating insulin sensitivity

EpoR(Phospho Tyr426) Polyclonal Antibody, 20ul Centrifuges The encoded protein is theThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce