EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator the encoded protein binds to

the encoded protein binds to the putative leucine zipper domain of macroH2A1

which catalyze the transfer of sulfate to HS

This protein contains one PH domain and one SH3 domain

Several transcript variants encoding different isoforms have been found for SHC1

The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin

EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator the encoded protein binds toThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.