Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges HNRNPK belongs to the subfamily

HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

It possesses both activation and repression domains| and it can therefore have both positive and negative effects on the transcription of target genes

This intronless gene encodes a member of the Kruppel-like family of transcription factors

The encoded protein may be involved in a wide range of biological processes including inflammation

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges HNRNPK belongs to the subfamilyThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.