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NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis MALT1 has been found to

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NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis MALT1 has been found toNBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number

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Description

MALT1 has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas

This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport

Environmental stress triggers Bim phosphorylation by JNK and results in its dissociation from the dynein complex and increased apoptotic activity

Expression of ADGRE5 may play a role in the progression of several types of cancer

where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors

NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis MALT1 has been found toNBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number

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