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Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The cytokine is a disulfide-linked

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Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The cytokine is a disulfide-linkedNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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Description

The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins)

The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections

KDR/Flk-1 and Flt-4 are members of the class III subfamily of RTKs containing seven immunoglobulin-like repeats in their extracellular domains

but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1

Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The cytokine is a disulfide-linkedNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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