FAK(Phospho Ser843) Polyclonal Antibody, 20ul Cell Biology as well as xenobiotic substrates

as well as xenobiotic substrates such as naphthalene and ethoxycoumarin

This gene and the WNT6 gene are clustered in the chromosome 2q35 region

MALT1 and this protein are thought to synergize in the activation of NF-kappaB

Studies in mouse show that this gene product functions as a transcription factor

it is not known whether this trimer is composed of one or more than one alpha chain isomer

FAK(Phospho Ser843) Polyclonal Antibody, 20ul Cell Biology as well as xenobiotic substratesThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal