Frizzled-3 Polyclonal Antibody, 50ul[BT-AP03359] Nucleic Acid Amplification This region is commonly deleted

This region is commonly deleted in chronic lymphocytic leukemia

Hyperglycemia increases the levels of diacylglycerol| which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia

Defects in this gene are a cause of dwarfism| while hypersecretion of the encoded protein is a cause of gigantism

and an inhibitor of HIV replication

This feature makes it ideal as a marker for use in fluorescence microscopy

Frizzled-3 Polyclonal Antibody, 50ul[BT-AP03359] Nucleic Acid Amplification This region is commonly deletedFZD3 is a member of the frizzled gene family. Members of this family encode seven transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. The function of Frizzled 3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript