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Catenin-Beta Polyclonal Antibody, 100ul[BT-AP01226] Low retention tips This protein was demonstrated to

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Catenin-Beta Polyclonal Antibody, 100ul[BT-AP01226] Low retention tips This protein was demonstrated toThe protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

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Description

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis

PubMed:97066971 and PubMed:9013614

enzyme regulation:Activated by phosphorylation on Ser-52 and Ser-588

This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif

Catenin-Beta Polyclonal Antibody, 100ul[BT-AP01226] Low retention tips This protein was demonstrated toThe protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.

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