NPL4 Polyclonal Antibody, 50ul Cell Culture & Maintenance |online information:Interleukin-17 entry|PTM:Found both in

|online information:Interleukin-17 entry|PTM:Found both in glycosylated and nonglycosylated forms

Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder

a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids

as well as cross-contamination

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NPL4 Polyclonal Antibody, 50ul Cell Culture & Maintenance |online information:Interleukin-17 entry|PTM:Found both inBinds ubiquitinated proteins via its RanBP2 type zinc finger.,The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4 UFD1L VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway: Protein degradation;