Rock-1 Polyclonal Antibody, 20ul Serum & Sample Tubes The protein binds 5S rRNA

The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP)

an autosomal dominant form of genetic hair loss

and malignant cells of bone and soft tissue sarcomas

A duplication of LMNB1 is associated with autosomal dominant adult-onset leukodystrophy (ADLD)

The level of mRNAs for this gene peaks in the G1 phase of the cell cycle

Rock-1 Polyclonal Antibody, 20ul Serum & Sample Tubes The protein binds 5S rRNAROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.