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MAGB3 Polyclonal Antibody, 50ul Pathway and Network Analysis N protein binds to viral

SKU: 33113097342

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MAGB3 Polyclonal Antibody, 50ul Pathway and Network Analysis N protein binds to viralThis gene is a MAGE B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE A subfamily are located in the Xq28 region, while the members of the MAGE B subfamily are clustered in the Xp21 region.

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Description

N protein binds to viral RNA and leads to formation of the helical nucleocapsid

Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot

May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs)

The protein undergoes two cleavage events

Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness

MAGB3 Polyclonal Antibody, 50ul Pathway and Network Analysis N protein binds to viralThis gene is a MAGE B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE A subfamily are located in the Xq28 region, while the members of the MAGE B subfamily are clustered in the Xp21 region.

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