LSP1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation mRNA surveillance detects exported mRNAs

mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD)

The protein encoded by CFLAR (CASP8 and FADD like apoptosis regulator) is a regulator of apoptosis and is structurally similar to caspase-8

and thus activated by JNK kinases

This gene is deleted in Williams-Beuren syndrome

• Two programs P1/P2

LSP1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation mRNA surveillance detects exported mRNAsLSP1 encodes an intracellular F actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.