Siah-1/2 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein constitutes a

The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved

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CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al

where it phosphorylates and inactivates BCKD

This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation| where it becomes a member of the nuclear factors of activated T cells transcription complex

Siah-1/2 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis The encoded protein constitutes aSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing