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PARP-4 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds thereby facilitating their endocytosis

SKU: 33075305599

4.4
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PARP-4 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds thereby facilitating their endocytosisPARP4 encodes poly(ADP ribosyl)transferase like 1 protein, which is capable of catalyzing a poly(ADP ribosyl)ation reaction. Poly [ADP ribose] polymerase 4 has a catalytic domain which is homologous to that of poly (ADP ribosyl) transferase, but lacks an N terminal DNA binding domain which activates the C terminal catalytic domain of poly (ADP ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may

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Description

thereby facilitating their endocytosis

GO annotations related to this gene include protein kinase binding and receptor tyrosine kinase binding

transcriptional repression and regulation of telomere length

This gene has been found to have multiple copies on many chromosomes

miscellaneous:Knockdown significantly reduces the adhesion of cancer cells to lung microvascular endothelial cells and the reciprocal effect is observed following overexpression

PARP-4 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds thereby facilitating their endocytosisPARP4 encodes poly(ADP ribosyl)transferase like 1 protein, which is capable of catalyzing a poly(ADP ribosyl)ation reaction. Poly [ADP ribose] polymerase 4 has a catalytic domain which is homologous to that of poly (ADP ribosyl) transferase, but lacks an N terminal DNA binding domain which activates the C terminal catalytic domain of poly (ADP ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may

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