STXB2 Rabbit Polyclonal Antibody, 20ul Subcellular Fractions Interleukin-33 encoded by IL33 is

Interleukin-33 encoded by IL33 is a cytokine that binds to the IL1RL1/ST2 receptor

a highly conserved protein complex that functions as an important regulator in multiple signaling pathways

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

predominantly with 60S large ribosomal subunits

which suggests a regulatory role in DNA replication during the S-phase of the cell cycle

STXB2 Rabbit Polyclonal Antibody, 20ul Subcellular Fractions Interleukin-33 encoded by IL33 isThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.