KLF8 Polyclonal Antibody, 50ul Pipette Filler heterodimerize with the related platelet-derived

heterodimerize with the related platelet-derived growth factor subunit A

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities

The protein also has rho-GTPase activity

They are plasma membrane proteins containing seven epidermal growth factor-like repeats

This receptor has various functions| including in the intracellular trafficking of lysosomal enzymes| the activation of transforming growth factor beta| and the degradation of insulin-like growth factor 2

KLF8 Polyclonal Antibody, 50ul Pipette Filler heterodimerize with the related platelet-derivedKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.