Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 20ul Bacterial Expression it may regulate DNA replication

it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53-dependent transcription

The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates

The protein encoded by this gene localizes to the nucleolus

ectopia lentis

Interacts with RRN3/TIF-IA

Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 20ul Bacterial Expression it may regulate DNA replicationVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone