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APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome The protein encoded by this

SKU: 29056002193

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APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome The protein encoded by thisAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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Description

The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex

the first step in the synthesis of GDP-fucose from GDP-mannose

Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor

then this is known to affect dendritic spine morphology and formation---this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway

Mutations in this gene are the most common cause of Fanconi anemia

APC Polyclonal Antibody, 100ul[BT-AP00506] Lysosome The protein encoded by thisAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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