MLL Polyclonal Antibody, 100ul Cell Culture Flasks Plec1 in mouse and rat)

Plec1 in mouse and rat) and the gene product had been referred to as "hemidesmosomal protein 1" or &qu

Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain

a single membrane-spanning region

Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons

This encoded protein was found to be abnormally expressed in patients with intractable epilepsy

MLL Polyclonal Antibody, 100ul Cell Culture Flasks Plec1 in mouse and rat)This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed